Pharmaceutical spray drying with LEWA diaphragm metering pumps

Pharmaceutical, biotechnological products, food or plant extracts for personal hygiene products and also fine chemicals dry fast through maximizing of the surface of the wet products.

LEWA diaphragm metering pumps from the hygienic und sanitary series in triplex design are perfect for reliable and safe metering in the spray drying process in the GMP environment.

Solutions

Advantages of LEWA diaphragm metering pumps for pharmaceutical spray dryers:

  • Hermetically sealed, no contaminants can get in or out
  • Easy-to-clean design, easy accessibility for maintenance purposes
  • High security thanks to 4-layer sandwich diaphragm with diaphragm monitoring and signaling without product contamination
  • Clean operation – no particle abrasion in the LEWA pump
  • Hygienic design, specially developed with and for the pharmaceutical industry (GMP-compliant)
  • Coating of spray dryer nozzles with constant pressure through a rigid pump curve
  • Gentle conveyance, no high shear forces
  • Low hold-up in the pump head thanks to design with minimized dead space
  • CIP; SIP; DIP
  • FAT, SAT and global service

Options:

  • Material 1.4435 (AISI 316L) with a surface roughness of Ra < 0.5µm
  • Inert and FDA compliant construction materials
  • Ex-proof protection, ATEX conformity
  • According to ASME BPE
  • Comprehensive documentation for qualification

LEWA is a member of leading committees for the hygienic design of pumps and systems.

QHD Certificate

QHD Certificate

Areas of application

LEWA metering pumps are used, for example, for:

  • Aqueous solutions, suspensions and emulsions
  • Compositions based on organic solvents, such as ethanol, isopropanol, acetone or methylene chloride

Filler, binder, disintegrants, sliding agents can thus be dissolved or suspended and transferred with the active material in defined, dry, free flowing, uniform particles.

Background

The fundamental concept of spray drying

The production of finely dispersed powder from a wet charging fluid by vaporizing the liquid:

  • A solution /suspension is sprayed via nozzles or rotating disk atomizers into a hot air or nitrogen flow
  • The supply to the spray drying system uses suitable pumps. Drying and particle formation are done simultaneously in the spraying process during this process. Due to these higher requirements on the pharmaceutical technology, the demands which are put on the bioavailability of a drug also increase. The effectiveness of a drug also depends on the generated particle size, after all.

Important customer requirements for this are:

  1. Particle size distribution
  2. Percentage of residual moisture
  3. Bulk density and particle shape
  4. Maintaining exact and consistent quality standards
  5. Precise, continuing, safe and
  6. low-pulsation fluid supply
Pharma Spray drying

Process scheme pharmaceutical spray drying

Industries

Pumps specially designed for the Cosmetics Industry
Cosmetics and personal care industry

Pumps and Systems for the Production of Personal Care Products

Processes with strict quality and hygiene requirements, such as GMP or the need to avoid preservatives, require the right equipment. We support you in the selection and the design of hygienic components and systems for producing personal care products. Contact our experts and let us advise you – we will work with you to develop customized metering solutions for your process, such as for manufacturing personal care products.

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LEWA pumps and systems meet the requirements of the Pharmaceuticals industry
Pharma and Biotech Industry

Pumps and Systems for the Pharmaceuticals, Life Sciences and Biotechnology Industries

As the leading manufacturer of pumps and pump systems for the pharmaceutical, life sciences, and biotechnology industries, LEWA supports you during the development of complete solutions, which meet your process requirements exactly. Special expertise is required in the production of pharmaceuticals in order to ensure that legal requirements are met. Reliability when it comes to production, documentation, and validation are our top priorities.

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Metering of sensible fluids in the food and beverage industry with LEWA pumps and systems
Food an beverages industry

Pumps and Systems for the Food and Beverage Industry

LEWA supports producers and plant construction companies in the food and beverage industries with pumps and systems for homogenization and dispersion, as well as for other processing operations in the food industry. We work with you to plan all the important process-related operations, such as conveying, metering, mixing, heating, and cooling so that you can process your raw product cost-effectively.

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Products

ecoflow sanitary hygienic pump

LEWA ecoflow® sanitary/hygienic diaphragm metering pump

LEWA ecoflow is also available in sanitary/hygienic. The metering pump for hygienic applications has the same all-around capabilities and fulfills all specifications for pharmaceutical and food production.

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LEWA ecodos sanitary/hygienic diaphragm metering pump

LEWA ecodos® sanitary/hygienic diaphragm metering pump

A sanitary/hygienic version is also available for the LEWA ecodos. Here, we meet all requirements for operation in pharmaceutical and food production.

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LEWA intellidrive diaphragm metering pump

LEWA intellidrive® diaphragm metering pump

Design the suction and discharge strokes of the metering pump to meet your specific requirements! With LEWA intellidrive technology, you can model pumping characteristics individually.

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LEWA ecoflow process pump

LEWA ecoflow® process pumps for high-pressure applications

The innovative ecoflow diaphragm process pump shows its strengths in high-pressure applications in the oil and gas, refinery and petrochemical industries as well as in the sensitive areas of pharmaceuticals, biotechnology, food and beverage production.

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LEWA triplex process pump

LEWA triplex® process pumps for high-pressure processes

The LEWA triplex process diaphragm pump is among the world's most compact high-pressure pumps and can even be set up in the tightest spaces when space is at a premium. The power package has proven its strength in numerous high-pressure processes in a variety of industries. 

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LEWA production units

Customer-Specific Metering, Mixing or Filling Systems from LEWA

Customer-specific batch/continuous systems for your production process. Metering, mixing, filling, separating, controlling temperature: We work with you to develop the ideal process-related sequence and produce the system that fits your production process – right up to the end product.

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LEWA customer specific metering systems

Customer-Specific Metering Systems from LEWA

Turnkey metering system in closed loop control with monitoring and plausibility testing equipment. Your individually configured metering system with an optimally designed pump for fluid metering in automated processes.

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LEWA triplex® homogenizing pump

The LEWA triplex homogenizing pump offers hermetic diaphragm technology for sensitive ready-to-drink products, infant food, nutraceuticals and enteral nutrition. It is ideally suited for the treatment of demanding fluids in the food, beverage and pharmaceutical industries.

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Keep in touch with us

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